Effectiveness of Bigdeli Neuro-Cognitive Learning in Improving Brain-Function Mapping Indicators Associated with Autism Spectrum Disorder
Keywords:
autism spectrum disorder, Bigdeli Neuro-Cognitive Learning, brain-function mapping, qEEG, neurocognitive intervention, hyperconnectivity, neuroregulationAbstract
Purpose: This study aimed to examine the effectiveness of Bigdeli Neuro-Cognitive Learning in improving EEG-based brain-function mapping indicators associated with ASD-related neurocognitive dysregulation.
Methods and Materials: A quasi-experimental pretest–posttest design with a control group was used. The sample included 66 participants with ASD-related symptoms, assigned to an intervention group (n = 33) and a control group (n = 33). The intervention group received six individual sessions of Bigdeli Neuro-Cognitive Learning over a three-month period, with sessions held approximately once every two weeks, while the control group did not receive the intervention. EEG-based brain-function mapping was conducted under open-eye conditions at pretest and posttest. The main outcomes included absolute and relative power indicators, high-beta activity, hyperconnectivity, and hypoconnectivity.
Findings: After controlling for baseline scores, the intervention group showed significantly lower posttest scores than the control group in absolute delta, absolute theta, relative delta, and hyperconnectivity. These findings indicate improvement in selected neurofunctional indicators related to slow-wave regulation and excessive connectivity patterns.
Conclusion: Bigdeli Neuro-Cognitive Learning may be a promising complementary intervention for improving selected brain-function mapping indicators associated with ASD-related neurocognitive dysregulation. However, future randomized studies with standardized behavioral ASD measures and follow-up assessments are needed.
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Copyright (c) 2025 Mojtaba Bigdeli Shamloo (Author); Hamid Kamarzarin; Mohana Mohammadi, Fatemeh Pirzal Mobarak (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
